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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
22.73
Human Site:
S546
Identified Species:
41.67
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S546
P
L
P
K
P
L
I
S
Y
I
R
K
F
Y
Y
Chimpanzee
Pan troglodytes
XP_512211
535
59559
S499
S
R
F
M
Q
V
R
S
L
Q
Y
L
C
R
F
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
Y326
V
G
R
P
L
I
S
Y
I
R
K
F
Y
Y
Y
Dog
Lupus familis
XP_548159
411
45633
S376
P
L
P
K
P
L
I
S
Y
I
R
K
F
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S544
P
L
P
K
P
L
I
S
Y
I
R
K
F
Y
Y
Rat
Rattus norvegicus
XP_001081372
564
60962
S529
P
L
P
K
P
L
I
S
Y
I
R
K
F
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
S482
S
R
F
M
Q
V
R
S
L
Q
Y
L
C
R
F
Chicken
Gallus gallus
XP_423895
264
29931
P230
T
P
V
Q
L
L
Y
P
V
S
R
F
S
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
V698
P
L
P
K
P
L
I
V
Y
L
R
K
F
Y
Y
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
S530
P
L
P
R
P
L
I
S
Y
L
S
K
F
Y
Y
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
P982
K
D
L
I
Q
T
L
P
L
P
R
R
L
L
D
Honey Bee
Apis mellifera
XP_397211
804
90105
D763
P
L
P
R
R
L
I
D
Y
L
S
T
P
H
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
T577
R
V
S
Q
L
F
K
T
P
R
R
K
S
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
6.6
13.3
N.A.
86.6
80
6.6
46.6
N.A.
13.3
P-Site Similarity:
100
20
33.3
100
N.A.
100
100
N.A.
20
20
N.A.
93.3
93.3
20
66.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
16
0
0
8
0
0
0
0
0
16
47
0
16
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
54
0
8
31
0
0
0
0
0
% I
% Lys:
8
0
0
39
0
0
8
0
0
0
8
54
0
0
0
% K
% Leu:
0
54
8
0
24
62
8
0
24
24
0
16
8
8
0
% L
% Met:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
54
8
54
8
47
0
0
16
8
8
0
0
8
0
0
% P
% Gln:
0
0
0
16
24
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
8
16
8
16
8
0
16
0
0
16
62
8
0
16
0
% R
% Ser:
16
0
8
0
0
0
8
54
0
8
16
0
16
0
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% T
% Val:
8
8
8
0
0
16
0
8
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
54
0
16
0
8
54
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _